Mesenchymal stromal cell-derived extracellular vesicles improve islet β-cell metabolic function via miRNA-mediated regulation of Ankyrin-B expression.
AIMS Mesenchymal stromal-cell-derived extracellular vesicles (MSC-EVs) improve islet function, which may be mediated in part through the delivery of microRNAs (miRNAs) to β-cells. To investigate the underlying mechanisms, we identified the most abundant MSC-EV miRNAs, their relative transfer to β-cells and the extent t...