Quantitative Proteomics Reveals CBX4 Promotes Cervical Cancer Cell Proliferation by Regulating PFKFB4
CBX4 is an E3 SUMO ligase involved in the initiation and progression of multiple malignancies. However, the molecular mechanism underlying the functional significance of CBX4 in cervical cancer (CC) cells remains unclear. Here, we used CRISPR/Cas9 genome editing to generate CBX4-knockout cell lines and found that CBX...