Open access
Sep 2026
Integrative single-cell and bulk transcriptomics define polyamine-associated cell states in acute myeloid leukemia and implicate CCT6A in polyamine homeostasis
Polyamine-active AML blast states have prognostic and immune relevance, while CCT6A is functionally linked to AML cell fitness and polyamine homeostasis.
Ai-Mei Feng, Xiao-He Chen, Fan Chen et al.
· Frontiers in Immunology · 0 citations