African swine fever virus (ASFV) pA137R is a key immune evasion protein known to target TBK1 and suppress the cGAS-STING pathway; however, whether it modulates type I interferon (IFN) signal transduction remains unknown. In this study, we investigated the role of the A137R protein (pA137R) in the JAK-STAT type I IFN si...
Zong-Yi Wu, H. Shao, Patrick Butaye et al.· Veterinary Microbiology· 0 citations
Avian pathogenic Escherichia coli (APEC) is an important cause of colibacillosis in poultry, and increasing antimicrobial resistance has highlighted the need for alternative preventive strategies. This study aimed to develop an O18-cross-reacting material 197 (O18–CRM197) glycoconjugate vaccine candidate using an Esche...
ABSTRACT In recent decades, multiple novel reassortant avian influenza viruses (AIVs) carrying internal genes derived from H9N2 viruses have emerged in poultry in China and have repeatedly caused human infections, highlighting the pivotal role of the H9N2 internal genes cassette in facilitating cross-species transmissi...
Zhi-Min Wan, Wen-Jie Jiang, Xu-Dong Cao et al.· Emerging Microbes and Infect...· 0 citations
It is demonstrated that a novel molecular marker, D347G in PA, determines the virulence of H9N2 in mice, posing a potential risk of H9N2 with D347G in PA for public health and highlighting the significance of continuing surveillance of H9N2 field strains.
Zhe-Hong Zhao, Ye Tian, Wenjie Jiang et al.· Virulence· 1 citation
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
