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Sep 2026

High-level surfactin production by Bacillus subtilis through integrated metabolic engineering and bioprocess optimization.

The integration of multi-level strain engineering with fermentation optimization thus established B. subtilis ATCC 6051a as an effective platform for high-level surfactin production and provides a practical framework for the development of efficient microbial surfactin production systems.

Ai Chen, Yu-Kang Xie, Min Liu et al. · 0 citations
Sep 2026

Engineering of central metabolism for high-yield 1,3-propanediol production using co-substrates by Klebsiella pneumoniae.

1,3-Propanediol is a versatile C3 diol serving as a key building block used in various industries. Klebsiella pneumoniae represents an attractive microbial chassis for 1,3-PDO production due to its endogenous 1,3-PDO and Vitamin B₁₂ biosynthetic pathways. However, low carbon flux and by-product formation remain bottlen...

Shao-Qi Sun, Ai Chen, Wen-Qi Wang et al. · 0 citations

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