Open access
Sep 2026
FHL1 Downregulation Is Specific to Cancer-Associated Fibroblasts and Linked to Reduced Chromatin Accessibility in Colorectal Cancer
Background/Objectives: Colorectal cancer (CRC) is among the most diagnosed malignancies and is a leading cause of cancer-related deaths globally. Beyond canonical CRC driver mutations, additional molecular alterations such as dysregulated gene expression and epigenetic reprogramming shape the disease behavior and may r...
Abdullah A. Alqasem, Waad Al-Burayk, Muneira Habjar et al.
· Genes · 0 citations