Author

Ahmed R. Ali

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Editorial Open access Sep 2026

Baxdrostat (Baxfendy®), a first-in-class aldosterone synthase inhibitor approved for adults with uncontrolled hypertension.

Despite the availability of multiple antihypertensive therapies, many patients remain unable to achieve adequate blood pressure control. Excess aldosterone is a key contributor to resistant and uncontrolled hypertension. Baxdrostat (Baxfendy®), a first-in-class selective aldosterone synthase (CYP11B2) inhibitor, was ap...

Ahmed R. Ali, Long-Qin Hu · Medicinal Chemistry Research · 0 citations

Review 2023

Journal of Population Therapeutics & Clinical Pharmacology

This study aimed to extract, purify, and prepare endolysin-hydroxyethyl to extract, purify, and prepare endolysin-hydroxyethyl for the treatment of acne.

H. E. Hussain, A. Abdulamir, I. Farhood et al. · Social Science Research Netw... · 0 citations

Sep 2026

Thieno[2,3-d]pyrimidine scaffold optimization for synergistic c-Met/STAT3 blockade: Synthesis, structure-activity relationships, in vitro potency, and apoptotic pathways in colorectal cancer.

Compounds 17d and 17e were found to be the most potent and exhibited significant anticancer activity across a wide range of cancer cell lines within the NCI-60 panel and are promising leads for further development of dual c-Met/STAT3 inhibitors for treating colorectal cancer.

S. I. El-Desouky, Hesham Haffez, Mohamed S. Nafie et al. · Bioorganic chemistry (Print) · 0 citations