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Author

Ahmed M. Ashour

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4 papers indexed here

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Open access Oct 2026

Global Trends and Regional Patterns in the Epidemiology of Substance Use Disorders in 1990–2023: A Secondary Analysis of the Global Burden of Disease 2023 Study

Background: Substance use disorders (SUDs) remain a major contributor to global morbidity and mortality, imposing substantial health, social, and economic burdens worldwide. Comprehensive assessments of long-term epidemiological trends across World Health Organization (WHO) regions remain limited. This study examined g...

Ahmed M. Ashour, Ali Alshahrani · 0 citations
Open access Aug 2026

Pregabalin-associated adverse drug reactions

Pregabalin is widely used for neuropathic pain, epilepsy, and anxiety disorders but has become increasingly associated with misuse and dependence. Understanding its global safety profile is essential to support pharmacovigilance and toxicovigilance efforts. This study aimed to characterize the pharmacological and toxic...

F. Alshehri, Ahmed M. Ashour, Nasser M. Alorfi et al. · 0 citations
Review Open access Aug 2026

A PRISMA-guided systematic review of pharmacogenetic anticancer clinical trials registered on clinicaltrials.gov

Pharmacogenetic approaches are increasingly being incorporated into anticancer clinical trials and may contribute to the advancement of precision oncology, however, broader global representation, larger late-phase trials, and more standardized biomarker integration remain necessary to support wider clinical implementat...

Ahmed M. Ashour, Aliah M. Alhayyan, Rawan Alhayyan · 0 citations
Open access Aug 2026

pH-Responsive Carboxymethyl Cellulose-Encapsulating Hesperidin–Selenium Nanoparticles Attenuate Paracetamol-Induced Acute Kidney Injury via Keap-1/Nrf2, NF-κB, and Mitochondrial Apoptosis Modulation

Paracetamol overdose is a major cause of drug-induced acute kidney injury (AKI), driven by oxidative stress, inflammation, mitochondrial dysfunction, and tubular apoptosis. This study evaluated the nephroprotective efficacy of pH-responsive carboxymethyl cellulose-encapsulated hesperidin-stabilized selenium nanoparticl...

Mohamed H. A. Gadelmawla, Khaled M. Alam-Eldein, A. Saleh et al. · 1 citation

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