A unified strategy for α-alkoxyalkyl radical generation via pinacol boronic ester precursors
A general method to generate α-alkoxyalkyl radicals from pinacol boronic ester precursors (R–Bpin) has been developed. These radical precursors are stable in air, easy to prepare, and readily accessible via Matteson homologation followed by a 1,2-metallate shift with a broad range of metal alkoxides. The key step is a...