Efficacy and safety of minocycline in acute ischemic stroke: an updated systematic review and meta-analysis with trial sequential analysis of randomized controlled trials
It is suggested that minocycline is biologically credible, but it did not demonstrate a consistent benefit in functional or neurological outcomes after AIS, and minocycline is viewed as a promising adjunct that now needs better targeted, biomarker-informed, reperfusion-aware trials rather than immediate universal use i...