Representation over Architecture: A Protocol-Controlled Attribution of Frozen ESM-2 Embeddings versus Encoder Design for Secondary Structure Prediction on CB513
Protein secondary structure prediction (PSSP) on the CB513 benchmark [30] has been near a plateau for close to a decade, and many recent models add protein language-model (pLM) representations on top of increasingly elaborate encoders. How much of a reported gain comes from the representation, and how much from the enc...