Paired Urinary Cytology and Targeted FGFR3 S249C/R248C Mutation Detection in Urine from Patients with Bladder Cancer: A Pilot Study
Background: Urinary cytology is routinely used as an adjunct to cystoscopy in the diagnosis and surveillance of urothelial carcinoma. Although it has high specificity for high-grade tumors, its sensitivity for low-grade papillary lesions is limited. Activating mutations in the fibroblast growth factor receptor 3 (FGFR3...