Adithya Karthik

Insertion-Ligation Reconstitution of Transmembrane Proteins for Functional Interfaces in Synthetic Cells.

In living cells, transmembrane (TM) proteins transduce extracellular cues across a lipid bilayer, a structure that is otherwise impermeable to high-molecular weight and charged molecules. Synthetic cells (SCs), lipid bilayer-based systems that offer complete control over composition and response, have emerged as attrac...