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Author

Adilbek Rajapov

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Review Open access Aug 2026

Epigenetic Rewiring and Context‐Dependent Therapeutic Vulnerabilities in Myeloproliferative Neoplasms

Myeloproliferative neoplasms (MPN) are shaped by epigenetic rewiring that extends beyond canonical JAK2V617F‐driven signaling. This review argues that context‐dependent chromatin states, not merely genetic lesions, determine disease trajectory, fibrotic transformation, and leukemic progression. We synthesize recent evi...

Amr Ali Mohamed Abdelgawwad El-Sehrawy, M. Al-Khreisat, Aziz Kubaev et al. · 0 citations

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