Figure 1 from BET Inhibition Synergizes with RLR Signaling to Enhance Tumor Immunogenicity and T-cell Recognition
BETi pretreatment sensitizes tumor cells to pIC-induced inflammation. A, Experimental setup for BETi pretreatment and pIC transfection of tumor cells. B, Protein abundance of phosphorylated IRF3 and (C) TBK1 in A375 cells after 72 hours of JQ1 or DMSO pretreatment and pIC transfection for 24 hours assessed by Western b...
Lucas Baldran-Groves, Rok Žiberna, Marc-Antoine Gerault et al.
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