Pediatric patients with cancer exhibit increased neutrophil extracellular traps and reduced active deoxyribonuclease I: diagnostic, prognostic, and therapeutic opportunities
Background Neutrophil extracellular traps (NETs) contribute to cancer progression; however, their value as systemic biomarkers and therapeutic targets in pediatric cancers remains unclear. Purpose To evaluate circulating NET markers as minimally invasive diagnostic and prognostic biomarkers in pediatric cancer and expl...