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Author

Abrar H. Qadri

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Review Open access Jul 2026

Beyond the structure-function paradigm: A comprehensive review of intrinsically disordered proteins

A cross-kingdom synthesis of disorder-based chromatin regulation is developed, demonstrating that bacterial nucleoid-associated proteins, plant transcription factors, and mammalian chromatin regulators share a conserved charge-regulatory logic, mediated by PTM-dependent mechanisms that dynamically couple environmental signals with genome organization.

Sami N.Al Harake, Said Btadini, Abrar H. Qadri et al. · 0 citations

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