Abhishek Kumar

A Comprehensive Review of Triple-Negative Breast Cancer and Recent Advances in Acridone Derivatives for Its Treatment

Triple-Negative Breast Cancer (TNBC) is an aggressive breast cancer, poorly responsive to drugs targeting hormone receptors in other breast cancer types. It is molecularly complex and aggressive, hindering therapy. Molecular characterization of TNBC has identified mutations and key signaling pathways in its develop...

Targeting neurovascular dysfunction in diabetic neuropathic pain: a review of mechanism-based pharmacotherapy beyond gabapentinoids

Synergistic approaches to Alzheimer's disease: exploring the combined efficacy of phytoconstituents and conventional drugs.

Neem derivatives in integrated control of vectors and pathogens of leishmaniasis: Current knowledge and computational insights for future perspectives

Leishmaniasis remains a major neglected tropical disease affecting millions of people worldwide, particularly in resource-limited regions where effective prevention and treatment options are often inaccessible. Current control strategies primarily rely on chemical insecticides for sandfly management and antileishmani...

Mechanistic Insights into IL-17 Pathway Modulation in Breast Cancer by Pteridaceae Bioactive Compounds: A Network Pharmacology and Molecular Docking Approach

Abstract Objective This study assessed the pharmacological prospects of Pteridaceae phytoconstituents using an integrated network pharmacology (NP) and computational molecular docking (MD) strategy. Materials and Methods Various peer-reviewed literature databases, including ScienceDirect, PubMed, Scopus, and Google Sch...