Open access
Sep 2026
Progressive behavioral and cognitive decline in Drosophila harboring AD-associated APOE4 variants
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder, and its incidence is rising rapidly with population aging. Pathologically, AD is characterized by the accumulation of amyloid-β (Aβ) plaques and hyperphosphorylated Tau neurofibrillary tangles. Human genomic studies have identified numerous risk...
S. Biglari, Eshani Yeragi, David Bamisaye et al.
· bioRxiv · 0 citations