Abel Santamaría

Transcriptional and epigenetic regulation of the cannabinoid receptor type-1 (CB1R) in health and disease: an overview.

The endocannabinoid system (ECS) is a highly plastic signaling network whose components are dynamically regulated in a context-dependent manner. Among its components, the cannabinoid type 1 receptor (CB1R), encoded by the CNR1 gene, is involved in multiple processes, including neuromodulation, neurodevelopment, metabol...

Thallium Neurotoxicity: An Integrative Update

Ongoing investigation into the effects of thallium (Tl) on the central nervous system (CNS) yields new insights into the mechanisms underlying its toxicity. Tl is a heavy metal possessing specific chemical features that can induce severe acute and chronic intoxications in humans upon environmental, occupational, acci...

Nrf2 and STAT3 Pathways in Protecting Against Methylmercury-Induced Oxidative Stress in Hypothalamic Neuronal GT1-7 Cells