Formulation and Evaluation of Controlled-Release Repaglinide Tablets Using Eudragit RS100 and Carbopol P974 NF Polymer Combinations
Repaglinide is a short-acting insulin secretagogue whose short half-life necessitates frequent dosing, compromising adherence. Controlled-release (CR) matrix tablets combining hydrophobic and hydrophilic polymers can sustain drug release and reduce dosing frequency. To formulate and evaluate CR repaglinide tablets us...