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Aayush Shah

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#protein folding Open access Oct 2026

Computational characterization of the uncharacterized human protein C17orf58 identifies a PCOLCE-like NTR domain and predicts a C-terminal mode of metalloproteinase binding

A substantial fraction of human proteins have no described function. C17orf58 (UniProt Q2M2W7; "UPF0450 protein C17orf58") is one of them: it has no experimental structure and no functional literature. Here I report a computational characterization of C17orf58 that combines structure prediction, structural homology sea...

Aayush Shah · 0 citations
#protein folding Open access Oct 2026

Computational characterization of the uncharacterized human protein C17orf58 identifies a PCOLCE-like NTR domain and predicts a C-terminal mode of metalloproteinase binding

A substantial fraction of human proteins have no described function. C17orf58 (UniProt Q2M2W7; "UPF0450 protein C17orf58") is one of them: it has no experimental structure and no functional literature. Here I report a computational characterization of C17orf58 that combines structure prediction, structural homology sea...

Aayush Shah · 0 citations

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