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Author

Aashna Sinha

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Review Open access Aug 2026

Viral modulation of angiogenesis through microRNA networks: Implications for cancer biology, biomarkers, and therapy.

Angiogenesis is essential for development, tissue repair, and vascular homeostasis, whereas dysregulated neovascularization contributes to chronic inflammation, ischemic injury, and cancer progression. Viral infections can reshape vascular programs through endothelial signaling, immune responses, metabolic stress, and...

Qamar Abuhassan, Waleed K. Abdulsahib, Sanan Thaer Abdalwahab et al. · 0 citations
Review Sep 2026

Nanotheranostics in orthopedic diseases: a critical review of molecular diagnostic-driven targeted therapeutics for personalized patient care.

INTRODUCTION Orthopedics could greatly benefit from nanotechnology, especially in drug delivery, bone tissue engineering, and implant design. Nanotheranostics represents a major step toward individualized treatment by combining diagnosis and treatment into a single nanoplatform. For orthopedic applications, nanocarrier...

Qamar Abuhassan, Husni Farah, M. Rekha et al. · 0 citations
Review Open access Aug 2026

Extracellular Vesicle-Based Approaches in Acute Myeloid Leukemia: Therapeutic Potential and Translational Challenges.

The biological roles, biomarker potential, therapeutic applications, and methodological challenges of EVs in AML are summarized and the priorities required for their future clinical development are highlighted.

G. Oriquat, Shaker Al-Hasnaawei, Hayjaa Mohaisen Mousa et al. · 0 citations
Review Sep 2026

Clinical translation of mRNA-based cancer vaccines for solid tumors.

Evidence from published clinical studies and 65 registered clinical trials on mRNA-based cancer vaccines are synthesized, summarizing key molecular principles, delivery strategies, clinical translation in solid tumors, and ongoing opportunities for future therapeutic development are summarized.

Zahraa A. Alkhafaje, M. H., Aniruddh Dash et al. · 0 citations
Review Open access Aug 2026

Exosomal Non-Coding RNAs: Emerging regulators of the tumor microenvironment in gastrointestinal and hepatobiliary cancers.

Overall, EV-ncRNAs represent promising mechanistic biomarkers and therapeutic targets, but rigorous source-specific validation and standardized analytical workflows are required before clinical implementation.

T. AlRamadneh, Waleed K. Abdulsahib, Sanan Thaer Abdalwahab et al. · 0 citations
Review Open access Aug 2026

Tumor‐Associated Macrophages in the Chemoresistant Microenvironment of Gastric Cancer: Key Mechanisms and Intercellular Crosstalk

Current evidence on TAM‐driven chemoresistance in GC is synthesized, highlighting the molecular interplay between TAMs, tumor cells, and stromal components and underscores the potential of TAM‐centric therapies to overcome resistance and improve clinical outcomes.

S. Abdul-Rahman, Abdulkareem Shareef, S. Jyothi et al. · 0 citations

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