Insertion outside the supersite in the N-terminal domain of the SARS-CoV-2 spike glycoprotein may contribute to evasion of neutralizing antibodies
Variants of the SARS-CoV-2 virus continue to evolve. Rapidly emerging mutations, particularly in the Spike glycoprotein, may increase transmissibility and infectivity, and also lead to evasion of the immune response. The Spike protein contains two immunodominant epitopes: NTD and RBD. Numerous neutralizing antibodies a...