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Author

A. Zavaliangos-Petropulu

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2 papers indexed here

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Sep 2026

Microstructural changes in deep gray nuclei following electroconvulsive therapy.

BACKGROUND AND PURPOSE Electroconvulsive therapy (ECT) is efficacious for the treatment of major depressive disorder. However, its underlying mechanism of action remains debated and may involve neurogenesis, changes in axon/synaptic density or glial cells. Restriction spectrum imaging (RSI) is an MRI technique that can...

Christopher G. Filippi, Matthew Yh Leung, A. M. Uluğ et al. · 0 citations
Open access Sep 2026

Electroconvulsive therapy modulates neurite density and free water in discrete white matter compartments in major depression

Abstract Electroconvulsive therapy (ECT) is the most effective treatment for severe or intractable depression. The disrupt–potentiate–rewire framework proposes that ECT’s therapeutic effects include neural remodeling. We used the neurite orientation dispersion and density imaging (NODDI) model to characterize ECT-relat...

A. Zavaliangos-Petropulu, Paloma Pfeiffer, Madeline Crawford et al. · 0 citations

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