Author

A. Yakovlev

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Open access Oct 2026

The Critical Clock: Time-Dependent Inflammation, Catabolism and Immunosuppression Syndrome Is Associated with ICU Mortality

Background/Objectives: Chronic critical illness (CCI) is increasingly recognized as a major challenge in intensive care, yet its definition remains heterogeneous. The triad of inflammation, catabolism, and immunosuppression (ICS) is central to proposed CCI pathophysiology, but the association between its changing compo...

V. Likhvantsev, L. Berikashvili, P. Polyakov et al. · Diagnostics · 0 citations

Open access Oct 2026

Critical Episodes of Inflammation, Catabolism, and Immunosuppression Define Mortality Risk in Chronic Critical Illness

Background/Objectives: A globally recognized definition of chronic critical illness (CCI) is lacking. Temporal criteria produce variable estimates, while pathophysiological models emphasize inflammation, catabolism, and immunosuppression (ICS). The relationship between ICS dynamics and mortality remains unclear. Method...

V. Likhvantsev, L. Berikashvili, P. Polyakov et al. · Journal of Clinical Medicine · 0 citations

Open access Aug 2026

Non-linear and spectral EEG dynamics as stage–specific biomarkers of neuropsychological recovery post-stroke

Introduction Resting-state electroencephalography (EEG) offers promising window into the neuroplastic changes underlying recovery after stroke. This longitudinal study aimed to characterize the stage-specific dynamics of non-linear (fractal dimension, FD) and linear (power spectral density, PSD) EEG metrics and to eval...

L. Mayorova, Anastasia Kushnir, A. Yakovlev et al. · Frontiers in Neuroscience · 0 citations