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Author

A. Vidal-Puig

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Open access Aug 2026

Distinct multi-omics signatures of clinical subgroups of type 2 diabetes define heterogeneous responses to an insulin sensitizer

It is shown that severe insulin-resistant diabetes (SIRD) is characterized by distinct miRNA profiles correlated with liver injury, and metabolic shifts in amino acids and primary bile acids, which define the distinct molecular signatures of T2D subgroups, facilitating the prediction of heterogeneous treatment response...

Ze-Hui Cao, Ruo-Lan Zhang, Hao-Nan Chen et al. · 0 citations

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