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Author

A. Tropsha

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#protein folding Open access Oct 2026

Serotype-Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno-Associated Viral Vectors.

Adeno-associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized. This study...

Arianna Minzoni, Shriarjun Shastry, Eduardo Barbieri et al. · 0 citations
Open access Aug 2026

Every Cure Knowledge Graph: A Unified Biomedical Knowledge Graph for Drug Repurposing

EC-KG is an interoperable, provenance-first KG which integrates RTX-KG2, ROBOKOP, and PrimeKG at the network-level, encapsulating over 7 million nodes and 81 million edges from 95 primary data sources, and has improved coverage of core biomedical entities, and captures complex biomedical mechanisms within its topology.

Piotr Kaniewski, E. K. Carter, Daniel J. Rhodes et al. · 0 citations

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