Open access
Jul 2026
Buildable linkers: Site-Specific Antibody-Drug Conjugates with Well-Defined Payloads 2308812
The benefits of creating a buildable drug scaffold that’s accommodating for achieving exact payload conjugated at a specific site on Trastuzumab are shown, which will enable all therapeutic antibodies to be conjugated in a uniform manner, accelerating the advancing field of ADC therapeutics.
Lisa Arvidson, Katarina Jovic-Dold, J. Halpern et al.
· Journal of Immunology · 0 citations