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Author

A. Sonina

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2 papers indexed here

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2027

Synthesis, crystal structure, pharmacophore analysis and molecular docking of monoterpene-isatin conjugates as potential SARS-CoV-2 PLpro ligands with in vitro antiviral evaluation

A series of novel conjugates combining monoterpenoid fragments (camphor, fenchone) with an isatin scaffold was designed as potential SARS-CoV-2 PLpro inhibitors. Molecular docking and pharmacophore analysis confirmed their ability to bind to the active site of PLpro. Single crystal of target compound 12 was grown, the...

V. Oreshko, S. Borisevich, K. Kovaleva et al. · 0 citations
Sep 2026

Synthesis of Chiral Nopinane‐Annelated Pyrazolo[3,4‐ b ]pyridines From 5‐Aminopyrazoles and Myrtenal

A series of 1‐aryl‐5‐aminopyrazoles was synthesized from 3‐iminobutanenitrile and substituted arylhydrazines under microwave irradiation (115°C–120°C) in ethanol, affording the target compounds in moderate to excellent isolated yields (28%–89%). Subsequently, the synthesized 1‐aryl‐5‐aminopyrazoles were reacted wit...

Olga I. Maleeva, A. Agafontsev, A. Sonina et al. · 0 citations

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