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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

A. Sobolevsky

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2 papers indexed here

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Open access Oct 2026

Vanilloid site-mediated TRPV3 activation by cannabidiol and potent inhibition by 14-deoxy-11,12-didehydroandrographolide

TRPV3 is a heat- and ligand-gated calcium-permeable ion channel, which is mostly expressed in the skin and plays important roles in skin physiology. Targeting TRPV3 with selective ligands represents a promising therapeutic strategy for the correction of cutaneous pathological processes. For the rational drug design and...

A. Kalinovskii, D. Osmakov, Yuliya V. Korolkova et al. · 0 citations
Open access Sep 2026

Tuning of AMPA receptor activation by inhibitory auxiliary subunits and epilepsy-associated disease mutations

AMPA receptors (AMPARs) facilitate excitatory neurotransmission and are implicated in neurological and neuropsychiatric disorders. Binding of the neurotransmitter glutamate triggers AMPAR activation, which is modulated by potentiating and inhibitory auxiliary subunits. While modulation by potentiating auxiliary subunit...

Thomas P. Newton, M. Yelshanskaya, Muhammed Aktolun et al. · 0 citations

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