Author

A. Skupin

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Open access Aug 2026

LRRK2-G2019S impairs astrocyte differentiation and triggers a senescence-like phenotype in Parkinson’s disease models

Data show that LRRK2-G2019S impairs astrocyte specification and predisposes to a senescent phenotype, which contributes to the acquisition of a senescent-like phenotype in Parkinson’s disease patients.

Lisa M. Smits, S. Magni, K. Grzyb et al. · npj Parkinson's Disease · 0 citations