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A. Singh

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Review Oct 2026

Herbal Therapeutics for Psoriasis: Molecular Mechanisms, Clinical Evidence, and Advanced Drug Delivery Strategies

Psoriasis is a chronic immune-mediated inflammatory skin disease characterized by keratinocyte hyperproliferation, impaired epidermal barrier function, and dysregulated cytokine signaling. Although conventional therapies have improved disease management, their long-term use is often limited by adverse effects, high...

Shatrudhan Prajapati, Shikha Yadav, A. Singh · 0 citations
Review Sep 2026

Lipid-based Nanocarriers for Neurodegenerative Disorders: Bridging Blood-brain Barrier Biology and Translational Drug Delivery.

INTRODUCTION Neurodegenerative disorders, including Alzheimer's, Parkinson's, Huntington's disease, and amyotrophic lateral sclerosis, remain difficult to treat because the Blood-brain Barrier (BBB) severely restricts therapeutic access to the central nervous system. This review evaluates BBB biology and the potential...

A. Singh, Shatrudhan Prajapati, Shikha Yadav et al. · 0 citations
Review Sep 2026

Integrating AI Technologies and Drug Therapies in the Fight against Dementia: A Review

The combination of artificial intelligence with traditional dementia treatment methods enables medical professionals to diagnose patients earlier, make better treatment decisions, and deliver customised care to individual patients.

Namrata Bhadauria, A. Singh, Niranjan Kaushik et al. · 0 citations
Review Sep 2026

siRNA and mRNA Therapeutics: A Comprehensive Review of Mechanisms, Delivery Strategies, Clinical Applications, and Future Directions in Precision Pharmacology.

Small interfering RNA (siRNA) and messenger RNA (mRNA) therapeutics represent transformative approaches in precision pharmacology, enabling targeted gene silencing and protein expression, respectively. This review provides a comprehensive analysis of their molecular mechanisms, delivery strategies, clinical application...

Ritu Dahiya, A. Singh, Pooja Mathur et al. · 0 citations
Review Aug 2026

FAK and PYK2 as Central Resistance Nodes in Non-Small Cell Lung Cancer: Signalling Crosstalk and Combination Therapeutic Strategies

Although FAK/PYK2-targeted monotherapy has demonstrated limited clinical efficacy, rational combination strategies involving EGFR tyrosine kinase inhibitors, MAPK inhibitors, chemotherapy, or immunotherapy have shown promising synergistic effects.

Shatrudhan Prajapati, Shabana Khatoon, A. Singh et al. · 0 citations
Review Jul 2026

Integrative Phytotherapy for Neurodegenerative Disorders: Bridging Traditional Botanicals, Bioactive Compounds, and Nanotechnology.

The synthesis of emerging evidence regarding the neuroprotective efficacy of phytotherapy is presented in this review, and the focus is on such traditional medicinal plants as Bacopa monnieri, Withania somnifera, and Centella asiatica.

Shatrudhan Prajapati, Shikha Yadav, A. Singh et al. · 0 citations

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