Psoriasis is a chronic immune-mediated inflammatory skin disease
characterized by keratinocyte hyperproliferation, impaired epidermal barrier function,
and dysregulated cytokine signaling. Although conventional therapies have improved
disease management, their long-term use is often limited by adverse effects, high...
Shatrudhan Prajapati, Shikha Yadav, A. Singh· Current Pharmacogenomics and...· 0 citations
INTRODUCTION
Neurodegenerative disorders, including Alzheimer's, Parkinson's, Huntington's disease, and amyotrophic lateral sclerosis, remain difficult to treat because the Blood-brain Barrier (BBB) severely restricts therapeutic access to the central nervous system. This review evaluates BBB biology and the potential...
A. Singh, Shatrudhan Prajapati, Shikha Yadav et al.· Current Neurovascular Resear...· 0 citations
The combination of artificial intelligence with traditional dementia treatment methods enables medical professionals to diagnose patients earlier, make better treatment decisions, and deliver customised care to individual patients.
Namrata Bhadauria, A. Singh, Niranjan Kaushik et al.· Current Signal Transduction...· 0 citations
Small interfering RNA (siRNA) and messenger RNA (mRNA) therapeutics represent transformative approaches in precision pharmacology, enabling targeted gene silencing and protein expression, respectively. This review provides a comprehensive analysis of their molecular mechanisms, delivery strategies, clinical application...
Ritu Dahiya, A. Singh, Pooja Mathur et al.· Current Gene Therapy· 0 citations
The synthesis of emerging evidence regarding the neuroprotective efficacy of phytotherapy is presented in this review, and the focus is on such traditional medicinal plants as Bacopa monnieri, Withania somnifera, and Centella asiatica.
Shatrudhan Prajapati, Shikha Yadav, A. Singh et al.· Current Pharmaceutical Biote...· 0 citations
Future studies must aim to design nanoparticles that maximize tumor uptake, incorporate predictive biomarkers, and optimize clinical utility and therapeutic efficacy to enhance translational success.
A. Singh, Shatrudhan Prajapati, Shikha Yadav et al.· Current Pharmacogenomics and...· 0 citations
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