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A. Shah

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Sep 2026

Insulin Dose-Adjusted Hemoglobin A1c Has Suboptimal Performance for Identifying C-Peptide-Defined Partial Remission: The SEARCH for Diabetes in Youth Study.

OBJECTIVE Insulin dose-adjusted hemoglobin A1c (IDAA1c = HbA1c [%] + [4 × total daily dose in units/kg/day]) ≤9 is widely used to define partial remission in pediatric type 1 diabetes and as an eligibility criterion or outcome in disease-modifying therapy trials. However, it has not been validated in U.S. youth. Becaus...

Michael L. Ferm, Xiao-Fan Huang, Charles G. Minard et al. · 0 citations
Jul 2026

Proteomic signatures of loss of glycemic control in youth-onset type 2 diabetes in the TODAY study.

Novel proteins involved in axon guidance, immune response, inflammation, and metabolism associated with LOGC in youth-onset T2D with proteins demonstrating consistent associations across the lifespan and proteomic platforms are identified.

K. Tommerdahl, Kristen R. Miller, Jian-Jun Liu et al. · 0 citations

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