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A. Sculean

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Review Open access Sep 2026

Understanding exosomes: A history of EV-erything.

BACKGROUND Extracellular vesicles (EVs), including exosomes, have emerged as fundamental regulators of cell-to-cell communication and are increasingly recognized for their therapeutic and diagnostic promise. While EV research has expanded remarkably over the past two decades, the discipline is rooted in a much longer h...

R. Miron, Paras Ahmad, A. Sculean · 1 citation
Review Open access Sep 2026

New technologies in oral reconstructive medicine: Consensus report of the AAP/OF/SEPA Workshop

Current regenerative approaches lead to long‐term stable outcomes at natural teeth as well as dental implant sites; novel technologies can benefit patients by enhancing longer‐term stability of teeth and implants to promote the health of the oral cavity and dentition.

Mariano Sanz, S. Ivanovski, J. Nart et al. · 0 citations
Review Open access Oct 2026

Ten years and beyond: Long-term dental implant survival, success, and biological health-A systematic review and meta-analysis.

Dental implants are highly durable in terms of retention, but high survival does not establish long-term biological health or true treatment success: success rates were lower and definition-dependent, and peri-implant disease showed substantial variability.

V. Moraschini, Krisztina Mikulás, J. A. Shibli et al. · 0 citations
Review Open access Aug 2026

Periodontitis and metabolic dysfunction-associated steatotic liver disease.

OBJECTIVE Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive phenotypes, have eme...

R. S. de Molon, E. D. de Avila, D. da Silva Barbirato et al. · 1 citation
Open access Oct 2026

Periodontal Treatment Restores Gingival Crevicular Fluid and Serum Periostin Levels.

BACKGROUND AND AIM To investigate the effect of periodontal treatment on periodontal inflammation and periostin levels in patients with severe periodontitis. METHODS This study included two groups (periodontitis and periodontally healthy), each comprising 24 individuals. Periodontal clinical parameters were recorded,...

Aysegul Sarı, O. Ozcan, F. Kaçmaz et al. · 0 citations
Review Open access Aug 2026

Understanding extracellular vesicles in antiaging.

EVs represent promising therapeutic agents and biomarkers in aging biology, with the potential to regulate multiple hallmarks of aging concurrently, and should be prioritized for successful antiaging interventions.

Paras Ahmad, N. Estrin, A. Sculean et al. · 0 citations
Review Open access Aug 2026

Individualized healing significantly improves pink esthetics around immediate single implants: A systematic review and meta-analysis.

AIM This systematic review and meta-analysis aimed to compare soft and hard tissue outcomes of applying anatomic healing abutments (AHA) and provisional restorations (PR) versus cylindrical healing abutments (CHA) on immediately placed single implants. MATERIALS AND METHODS Four databases (PubMed, Embase, Cochrane, a...

Xinyi Qian, Boldizsár Vánkos, G. Agócs et al. · 0 citations
Open access Aug 2026

Smart Coatings Integrating Antimicrobial and Tissue-Remodeling Functions for Implant Interfaces.

The multifunctional coating provides sustained antimicrobial activity alongside immunomodulatory and pro-regenerative effects, supporting its potential to treat implant-related infections while enhancing peri-implant soft tissue remodeling.

Mariana Martins Guerreiro, Amanda Paino Santana, D. M. Cunha et al. · 0 citations

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