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A. Sankar

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Open access Sep 2026

Association of Polygenic Risk Score for Suicidal Behavior With Ventral Prefrontal Morphology in Bipolar Disorder.

BACKGROUND Bipolar disorder (BD) studies consistently implicate the ventral prefrontal cortex (VPFC) in association with suicidal behaviors. A suicidal behavior polygenic risk score (PRS) can now be computed to test whether elevated genetic risk for suicidal behavior is associated with variation in VPFC gray matter and...

Noa Katz Shroitman, D. Levey, Brian P. Pittman et al. · 0 citations
Open access Sep 2026

733. Effects of early life adversity on stress markers and emotion circuitry in adults with a history of suicide attempts

Findings partially support the stress system hormones as a biopsychosocial feature of recent SB and highlight dispositional factors as potential psychobehavioral treatment targets for broader vulnerable populations.

L. Colic, A. Sankar, A. Zerekidze et al. · 0 citations
Open access Sep 2026

674. Cognitive and neurobiological indicators of risk and prognosis in mood disorders

Abstract Background Mood disorders are major contributors to the global burden of disease. There is a critical need for reliable markers that can identify individuals at elevated risk for developing mood disorders and predict poor prognosis among those already affected, in order to guide personalized interventions. Aim...

A. Sankar, B. Ozenne, V. Dam et al. · 0 citations
Open access Sep 2026

529. **Rafaelsen Award Presentation** Cognitive function and the risk of later onset of depression in healthy individuals: a 10-year longitudinal study

Abstract Background Cognitive impairments are common in individuals with depression, but their role in the etiology of the disorder remains unclear. Aims & Objectives In this 10-year longitudinal study, we tested whether cognitive function is associated with a risk for developing future first-episode depression in indi...

A. Sankar, B. Ozenne, V. Dam et al. · 0 citations
Open access Aug 2026

Cortical Thickness in Middle and Older Aged Adults With Bipolar Disorder Across Six International Sites

Older adults with bipolar disorder (BD) are at high risk for severe mood symptoms, cognitive difficulties, and early mortality; however, underlying brain alterations have received little study. Gray matter decreases in ventral prefrontal cortex (VPFC) seen in younger persons with BD, and additionally in dorsal PFC (DPF...

Rebecca B. Marks, A. Sankar, L. Colic et al. · 0 citations

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