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A. S. Fattakhova

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Open access Oct 2026

The impact of BRAF mutation on survival of patients with metastatic colorectal cancer depending on the type of surgical and systemic treatment

Introduction . Metastatic colorectal cancer (mCRC) remains a leading cause of cancer-related mortality worldwide. BRAF mutations (predominantly V600E) occur in 5–10% of mCRC cases and are associated with an aggressive disease phenotype, poor response to conventional chemotherapy, and dismal prognosis. In the Russian...

A. S. Fattakhova, S. V. Cheporov, N. P. Shiryaev · 0 citations

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