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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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A. Ruszkowska

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Open access Sep 2026

Bridging the antiviral gap: A BAC-based non-infectious SARS-CoV-2 replicon reveals potent antisense gapmers

A non-infectious SARS-CoV-2 replicon, pBAC-SARS-CoV-2_S/eGFP_ΔE, was developed and evaluated antisense gapmers targeting RNA structural motifs within the untranslated regions (UTRs) and nucleocapsid (N) and membrane (M) genes, suggesting that dual targeting may be an effective antiviral strategy.

A. Ruszkowska, Agnieszka Baliga-Gil, Julita Piasecka et al. · 0 citations

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