Background: Female sex is widely regarded as an independent risk factor for adverse outcomes after conventional coronary artery bypass grafting (CABG) and is incorporated as a risk variable in EuroSCORE II. Whether this disadvantage persists in the setting of minimally invasive direct coronary artery bypass (MIDCAB), i...
L. Amanov, Arian Arjomandi Rad, Sadeq Ali-Hasan-Al-Saegh et al.· Journal of Clinical Medicine· 0 citations
The functionality of tissue-engineered cardiac constructs using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is challenged by the cells' immature state. To promote cell and tissue maturation, co-culture approaches, mechanical, electrical and topographical stimuli have been applied. Here, large...
Sara Szadocka, Jana Teske, A. Franke et al.· Biofabrication· 0 citations
ABSTRACT Lung transplantation is the only long‐lasting life‐saving treatment for patients with end‐stage pulmonary disease, but the ever‐growing shortage of suitable donor organs leads to high mortality rates of the afflicted patients. Xenotransplantation, the transplantation of organs across species, has emerged as a...
N. Roters, Niveditha Varma, R. Ramm et al.· Xenotransplantation· 0 citations
This study demonstrates the successful production and injection of human induced pluripotent stem cell cardiomyocyte aggregates into infarcted cynomolgus monkey hearts, resulting in substantial, structured human grafts three months after cell transplantation, and uncoupling of cardiomyocyte production from transplantat...
I. Gruh, Andreas Martens, S. Cebotari et al.· Nature Communications· 0 citations
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