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Review Open access Oct 2026

Clinical efficacy and safety of Malaria vaccines in children: a systematic review and meta-analysis

Abstract   Malaria remains a global public health emergency with high mortality especially among children under 5 years. Despite increased research on pediatric malaria vaccines, comprehensive evidence syntheses are limited. We aimed to assess the efficacy and safety of currently available malaria vaccines in children....

K. Bashlakova, M. Zarro, P. Villari et al. · 0 citations
Review Open access Sep 2026

Clinical efficacy, immunogenicity and safety of RTS,S/AS01, R21/Matrix-M and candidate malaria vaccines in children: A systematic review and meta-analysis.

RTS,S and R21 vaccines achieve the highest efficacy particularly in combination with SMC and should be integrated into childhood malaria control strategies emphasizing the need for booster strategies and long-term effectiveness monitoring in endemic settings.

K. Bashlakova, M. Zarro, Paolo Villari et al. · 0 citations

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