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Author

A. Rodríguez-Vida

2 papers indexed here

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Open access Oct 2026

Talazoparib plus enzalutamide in high-volume metastatic hormone-naive prostate cancer: a randomized phase 2 trial.

Combining inhibition of poly(ADP-ribose) polymerase and androgen receptor (AR) pathway has demonstrated clinical activity in men with metastatic prostate cancer, although the extent of benefit in tumors lacking homologous recombination repair (HRR) gene alterations remains uncertain. We conducted a randomized phase 2 t...

F. Zacchi, Elena Castro, Kathleen Imbach et al. · 0 citations
Clinical trial Open access Sep 2026

Phase 1 study of KHK2455, a long-acting, potent and selective IDO1 inhibitor, in combination with avelumab in patients with locally advanced or metastatic urothelial carcinoma

The favorable safety profile and preliminary efficacy results of KHK2455 in combination with avelumab, along with the translational biomarker findings, warrant further investigation.

Y. Zakharia, B. D. D. de Spéville, R. Morales-Barrera et al. · 0 citations

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