Jul 2026
Insights into novel benzo[h]quinoline-based 2-thioxothiazolidin-4-one and thiazol-4-one hybrids as potential antimicrobial, and antibiofilm candidates: Design, synthesis, molecular modeling, and in-silico ADME studies.
The findings strongly confirm the substituted benzo[h]quinoline core as a highly promising pharmacophore for the development of next-generation antimicrobial medicines effective against both free-floating planktonic cells and tough structured biofilms.
Reham R Raslan, S. Eissa, Moustafa S. Abusaif et al.
· Bioorganic chemistry (Print) · 0 citations