The Oral–Gut–Systemic Axis in Periodontitis: Microbiome Dysbiosis, Immune Crosstalk and Translational Perspectives
Periodontitis is a chronic inflammatory disease associated with subgingival dysbiosis and altered host response. Although it is usually considered a local disease of the tooth-supporting tissues, it may also interact with distant mucosal and systemic compartments. One possible explanation is the oral–gut–systemic axis....