A. Qadir

Metabolic memory in diabetes: decoding the molecular basis of persistent cellular programming for next-generation therapeutic strategies

Hypothyroidism and Metabolic Dysfunction–Associated Steatotic Liver Disease: Mechanisms, Clinical Links, and Therapeutic Implications

The Redox Imbalance in Cancer: Targeting Glutathione and Thioredoxin Systems to Enhance Chemotherapy Response

Sucralose and Human Health: Metabolic, Microbiome, Neuroendocrine, Toxicological, and Environmental Perspectives

Sucralose is a prevalent non-nutritive sweetener characterised by its chemical stability, intense sweetness, and low-calorie content, which have facilitated its global acceptance, regulatory endorsement, and an acceptable daily intake (ADI) of 5 mg/kg. However, recent data question its presumed inertness and undersco...

Saccharin Revisited: Chemistry, Metabolism, Toxicology and Human Health Risk Assessment in the Era of Evidence-Based Food Safety.

A comprehensive and critical synthesis of current knowledge on saccharin, encompassing its chemical characteristics, physicochemical properties, industrial and pharmaceutical applications, absorption, metabolism, excretion and toxicological profile is provided.

Dyslipidaemia: Pathophysiology, Epidemiology, Diagnostic Advances, and Emerging Therapeutic Strategies

This review elucidates the complex pathophysiology, epidemiological dynamics, and genetic architectures defining dyslipidaemia, delineating primary hereditary molecular defects from secondary acquired etiologies and discusses persistent barriers to patient adherence and the transformative potential of precision medicin...