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Advances in non-invasive neurophysiological techniques, intraoperative recordings, and connectome-based neuroimaging have provided new insights into how DBS modulates these pathological networks.
This work proposes a biology-driven clustering in a large cohort if subjects with iPD if subjects belonging to the ''Mixed Pathology'' subtype included subjects whose biomarker signature did not indicate predominant alterations in any of the explored pathways.
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