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Author

A. Pavlopoulou

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Open access Sep 2026

Network-guided identification and multi-targeting of cell cycle regulatory hubs in obesity-linked colorectal cancer

By shifting from a "one-target, one-drug" model to a systems-level approach, the proposed MTDL and its natural analogs represent promising candidates for experimental validation in the treatment of complex, obesity-associated CRC.

Merve Uça Apaydın, Huseyin Guner, Resat Unal et al. · 0 citations
Open access Aug 2026

Comprehensive Analyses of SOX7 Provide Novel Insights on Its Tumor Suppressor Role and Its Target Genes with Therapeutic Implications in Multiple Myeloma

Results indicate that SOX7 functions as a tumor suppressor in MM, and its inactivation promotes cell cycle progression, and the anti-myeloma effects of panobinostat in MM.1S cells may be partially mediated through SOX7 induction.

Arda Ceylan, Xiao-Zhou Hu, Tevfik Hatipoğlu et al. · 0 citations

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