A. Panov

Mitochondrial Cristae as Separate Compartments: Linking Organization and Function

This work describes a multi-stage transport pipeline—the TH–isocitrate dehydrogenase axis—wherein matrix-generated reducing equivalents are exported into the cytoplasm via an irreversible isocitrate/α-ketoglutarate loop and highlights the role of compartmentalization in ATP transport and utilization processes.