Author

A. Oni-Orisan

2 papers indexed here

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Oct 2026

Distribution of the J1 haplotype variant rs2267439 across CYP2D6 diplotypes and its impact on risperidone metabolism.

CYP2D6 is a highly polymorphic pharmacogene responsible for the metabolism of more than 20% of commonly prescribed drugs. Clinical implementation of CYP2D6 pharmacogenetics relies on star allele nomenclature and the Activity Score system, yet substantial interindividual variability in drug exposure remains unexplained....

Antonio Asensi-Cantó, Wendy Y. Wang, Erin C. Boone et al. · Pharmacogenetics & Genomics · 0 citations

#protein folding Open access Sep 2026

MIR192 upregulates GLP-1 receptor and rescues statin-induced impairment of insulin secretion

Statins are a commonly prescribed cholesterol-lowering drug class that can increase the risk of new-onset diabetes (NOD). The underlying molecular mechanisms have yet to be fully elucidated. We aimed to identify molecular factors associated with differential susceptibility to NOD and determine their effects on β-...

Yu-Lin Kuang, C. Locatelli, Yu-Qing Zhang et al. · Cardiovascular Diabetology · 0 citations