Author

A. Onar-Thomas

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

A Phase I Trial of the ADAM-10 inhibitor, INCB007839, in Children with Recurrent/Progressive High-Grade Gliomas: A Report from the Pediatric Brain Tumor Consortium (PBTC-056)

Pediatric high-grade gliomas (pHGGs), including diffuse midline glioma (DMG) and diffuse intrinsic pontine glioma (DIPG), are the leading cause of central nervous system tumor-related morbidity and mortality in children. Neuronal activity promotes pHGG growth; one key mechanism is neuronal activity-regulated shed...

Alicia C. Lenzen, Sonia Partap, C. Billups et al. · Neuro-Oncology Pediatrics · 0 citations

Open access Aug 2026

Cell autonomous regional differences in oligodendrocyte lineage development and responses to oncohistone H3.3 K27M

It is suggested that histone H3.3 K27M mutations drive diffuse midline glioma by ablating intrinsic regional differences in oligodendrocyte development, selectively expanding immature oligodendrocyte precursor cell populations in the brainstem while disrupting normal differentiation programs.

Jared M. Andrews, K. Budd, C. Kwon et al. · Nature Communications · 0 citations