Open access
Sep 2026
KMT5A maintains muscle stem cell quiescence through epigenetic regulation of Notch signaling
This work shows that the H4K20 monomethyltransferase KMT5A sustains canonical Notch signaling in quiescent MuSCs through catalytic deposition of H4K20me1, indicating that H4K20me1 supports transcriptional competence at Notch loci.
J. Hwang, A.-O. Chu, Roméo S. Blanc
· iScience · 0 citations